Activelle 28 tablets

Category: Hormones (HRT)
Price $22

17 September 2022

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Activelle (28 Tablets)

Contain the active ingredient: Estradiol hemihydrate 1 mg, Norethisterone acetate 0.5 mg

Description of the drug:

Estradiol and Norethindrone Acetate are the main active pharmaceutical ingredients present in Activelle 1 mg + 0.5 mg tablet. The medicine is a combination of two female hormones Estrogen  and progestin produced by the ovaries. It is a hormone replacement therapy, used by a women that help in reducing the symptoms of menopause such as hot flashes and vaginal dryness, these symptoms occur due to the less estrogen produced by the body. The progestin present in this medicine, helps to reduce the risk of cancer of the uterus, which can be caused by using estrogen alone. Each tablet of Activelle contains 1 mg of Estradiol and 0.5 mg of Norethindrone Acetate.

 

Indications and Usage:

The combination drug is mostly used as a hormone replacement treatment in menopausal women, who still have their uterus. Estradiol is an Estrogen and Norethindrone is a Progestin, both are female sex hormones. This drug is indicated to be used by the women in order to treat hot flushes, who are experiencing menopause. This medicine is also used to prevent osteoporosis, replace estrogen in women with ovarian failure, or as part of a cancer treatment regimen. It works by replacing a natural progestin and estrogen in women who can no longer produce enough of these hormones.

 

Dosage and Administration

-Recommended dose:

The dose may vary according to the patient condition therefore it is advised to take this medicament as per your doctor’s direction.

 

-Method of Administration:

Activelle is available in the form of a tablet taken orally by mouth, usually once a day with a glass of water. Do not break, crushed, or chew the tablet, it will cause you a bitter taste.

 

-Missed dose:

If you miss one or more doses; take the next dose on time. If not taken on time it will increase the risk of becoming pregnant. It is advised to talk to your doctor and do not take more than your doctor is prescribed.

 

-Overdose:  

The overdose of any drug can cause severe effects. The overdose symptoms may include extreme drowsiness, agitation, aggression, shallow breathing, weakness, fainting, headache, vomiting and many other allergic symptoms. In the case of an overdose, you should immediately contact your doctor.

 

Forms and Strengths:

The drug Estradiol and Norethindrone Acetate is available on our website in the following strength and forms under the brand name of:

 

Activelle (1 mg+ 0.5 mg) Tablet

 

Contraindications:

-This drug should not be used in patients with known or suspected hypersensitivity to any of the ingredients present in the formulation

-This drug should not be used in pregnant  women. It may harm the unborn baby

-This drug should not be used in lactating women, using this medicine while breastfeeding is harmful to the new born baby as this drug may pass through the breast milk.

-Do not use this medication if the patient has had a cancer, such as breast cancer or a cancer of the womb lining or ovary

-This drug should not be used in women, who are suffering from unexplained abnormal vaginal bleeding

-Do not use this medication if you are having the habit of smoking and are older than 35 years of age.

-This medicine should not be used in those patients, who is having the highest risk of venous or arterial thrombosis diseases.

-This drug should not be given to those women who are suffering from uncontrolled high blood pressure, a heart disease, a blood clotting disorder

-This drug should not be used in those women, who have had their uterus removed because they do not need the progestin and therefore should not use this combination medication

-This medicament is contraindicated for the male patients

 

Warnings and precautions

-Using estrogen alone may increase the chances of getting cancer of the uterus. If you experienced any vaginal bleeding, which is undiagonosed. Vaginal bleeding after menopause may be a sign of cancer, therefore in this case contact your doctor immediately.

-If a patient is suffering from any kind of liver and kidney problem, including dialysis treatment, mental disorder such as depression, this drug is harmful in these conditions, therefore, it is advised to consult your doctor and let him know about your medical history prior taking this drug.

-If the patient is suffering from Thrombosis. Thrombosis is the formation of a blood clot in a blood vessel such as deep venous thrombosis or the lungs such as pulmonary embolism. In these conditions this drug should not be consumed without consulting the doctor. It is advised to take this drug only after consulting and prescription of the doctor.

-This drug is not suitable, if the patient is suffering from jaundice. Consult your doctor before taking this medicament.

-This drug is not suitable for those patients having a heart problem like angina, high blood pressure, or a heart attack. Consult your doctor first, if you have any kind of heart problem before taking this medication.

-This drug is not suitable for those patients who are suffering from asthma, diabetes, migraine or an epilepsy problem. In these conditions, consult your doctor before taking this medicament.

-This drug is not suitable for those patients, if they ever had bleeding in the brain, stroke, heart attack, or other serious blood vessel problems. In this case, consult your doctor before taking this medicament.

-This drug is not suitable for those women who have a history of breast nodules, fibrocystic disease of the breast, an abnormal breast x-ray or mammogram, or irregular or scanty menstrual periods. Consult your doctor before taking this medicament.

-If the patient has reported any kind of allergic reaction in the past with any kind of food, dyes, or medicines, then consult your doctor before applying this medicament.

-This drug is not suitable, if the patient is having any blood problem.

-This drug is not suitable for those patients, having surgery or will be confined to a bed or a chair for a long period of time. Consult your doctor regarding the same prior taking this medicine.

-This drug is not suitable for those patients, suffering from tuberculosis. Consult your doctor, let him know about your medical problem before taking this medicament.

-This drug is not suitable for those patients, who are overweight, having a high cholesterol  level or triglycerides, or having a fluid retention or a swelling problem. Before taking this drug, consult your doctor regarding your medical problem.

-This drug is not suitable for those women, who are suffering from any kind of cancer. It is advised to tell your doctor about your disease before taking this medicament.

-If the patient has reported any kind of allergic reaction in the past with any kind of food, dyes, or medicines, then consult your doctor before applying this medicament.

Use this drug with caution in elderly patients, older adults may be more sensitive to the side effects of this drug.

Before buying  Activelle tablets (1 mg + 0.5 mg) online, it is necessary to do a thorough research on its ingredients.

 

Side effects

Tell your doctor if you have any side effects that bothers you or does not go away.

 

Some common side effects that can occur:

Changes in menstrual bleeding, eg., irregular bleeding or sometimes stopping of bleeding.

-Mood changes, including depression.

-Decreased sex drive 

-Headache

-Nausea.

-Acne.

-Breast tenderness.

-Weight gain.

-Rash or hives.

-Ectopic pregnancy

 

Some rare side effect can occur which will be serious:

-Fever

-Shortness of breath

-Blurred vision

-Jaundice

-Mood swings

-Vaginal discharge

-Weight gain

-Hair loss

-Cysts on the ovaries

-Painful menstrual cycle

-Acne

-Less sexual desire

-Migraine

-Signs of blood clot

-Irritation or itching of the skin in or around the vagina.

-Breasts become swollen, tender or painful

-Burning off your skin

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